Clinical Trial Simulation
The current situation
Conducting successful clinical trials is the most important aspect of the product development process for pharmaceutical, biotechnology, diagnostic, and medical device companies. Clinical trials require a significant investment of time and resources, and failure to achieve an appropriate event rate may require costly trial expansion or potential trial extension.
The Archimedes advantage
The Archimedes Model is a comprehensive, validated simulation model of human physiology, diseases, behaviors, interventions, and healthcare systems. It has been in development since 1993 and has demonstrated its value to more than 90% of the top pharmaceutical organizations worldwide.
By simulating clinical trials before committing to their execution, companies can:
- Quantify expected event rates to ensure their studies are sufficiently powered
- Avoid potentially costly errors and mitigate risk by reducing the uncertainties in powering a trial
- Improve a trial’s probability success
How you can use the Archimedes Model
ARCHeS Innovator. ARCHeS Innovator is a comprehensive web-based tool that gives you access to the Archimedes Model and enables you to simulate clinical trials relating to cardio-metabolic risk. For each simulation, ARCHeS gives you the power to specify:
- Inclusion and exclusion criteria based on key patient characteristics and biomarkers
- Baseline characteristics for a population
- Treatment for cardio-metabolic conditions including antihypertensive agents, cholesterol treatments, and interventions for obesity and smoking
ARCHeS Innovator can also be used to create new or hypothetical treatments, either by drawing from the results of phase 2 clinical trials or by specifying effects on biomarkers and/or health outcomes. More...
Modeling & Consulting Services. Archimedes provides comprehensive support to help you run custom clinical trial simulations. For questions beyond the scope of ARCHeS Innovator, our team of scientists and physicians can work with you to develop objectives, design simulations to answer the questions of interest, and analyze and interpret the data. More...
